Methadone is contraindicated rein patients with a known hypersensitivity to methadone hydrochloride or any other ingredient rein methadone hydrochloride tablets.

Methadone may Beryllium expected to have additive effects when used rein conjunction with alcohol, other opioids, or illicit drugs that cause central nervous system depression. Deaths associated with illicit use of methadone frequently have involved concomitant benzodiazepine abuse.

For women Weltgesundheitsorganisation are breastfeeding: Methadone may pass into breast milk and may cause side effects hinein a child who is breastfed.

The total daily dose of methadone on the first day of treatment should not ordinarily exceed 40 mg. Dose adjustments should be made over the first week of treatment based on control of withdrawal symptoms at the time of expected peak activity (e.g., 2 to 4 hours after dosing). Dose adjustment should Beryllium cautious; deaths have occurred in early treatment due to the cumulative effects of the first several days' dosing. Patients should be reminded that the dose will “hold” for a longer period of time as tissue stores of methadone accumulate.

In the selection of an initial dose of methadone hydrochloride tablets, attention should be given to the following:

Overdose rein children warning: Children Weltgesundheitsorganisation accidentally take this drug have a high risk of death from overdosing. Children should not take this drug.

Read the Patient Information that comes with methadone hydrochloride tablets before you take it and each time you get a new prescription.

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Do not take any medicine while using methadone hydrochloride tablets until you have first talked to your doctor or pharmacist. They will Beryllium able to tell you if it is safe to take other medicines while you are using methadone hydrochloride tablets.

Rein using methadone an individualized benefit to risk assessment should Beryllium carried out and should include evaluation of patient presentation and complete medical history.

Do not change your dose unless your doctor tells you to change it. Do not take a higher dose of methadone hydrochloride tablets or take it more often than prescribed. This can lead to an overdose and possibly death.

Physicians should individualize treatment hinein every case (see DOSAGE AND ADMINISTRATION), taking into account the high degree of interpatient variability hinein response to and metabolism of methadone.

Clinical studies of methadone did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently Methadontabletten online kaufen compared to younger subjects. Other reported clinical experience has not identified differences in responses between elderly and younger patients.

For people with liver problems: If you have liver problems or a history of liver disease, you may not be able to process this drug well. This may increase the levels of methadone rein your body and cause more side effects. Your doctor should watch you closely if you take this drug.